The domain memory had a significant added prognostic value in HGG as indicated by an LRT ( p-value = 0.018). Results: We included 109 LGG and 145 HGG patients with a median survival time of 1,490 and 511 days, respectively. We compared Cox proportional hazards regression models with and without the cognitive domain by means of loglikelihood ratios tests (LRT), discriminative performance measures (by AUC), and risk classification. Their added prognostic value on top of known prognostic factors was assessed in two patient groups ).
Methods: In a retrospective cohort study of patients undergoing awake craniotomy between 20 we performed pre-operative neuropsychological assessments in five cognitive domains. Our aim was to investigate whether pre-operative cognitive functioning is of added value in survival prediction in these patients.
Background: Diffuse gliomas, which are at WHO grade II-IV, are progressive primary brain tumors with great variability in prognosis.
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